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Brimonidine is an α 2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. [4] [5] In rosacea it improves the redness. [5] It is used as eye drops or applied to the skin. [4] [5] It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate. [6]
Brinzolamide works by blocking an enzyme called carbonic anhydrase, which produces bicarbonate needed for the production of the aqueous humour, while brimonidine tartrate blocks another enzyme known as adenylate cyclase, which is also involved in the production of the aqueous humour. [4]
A systematic review examined the benefits and clinical efficacy of routine skin care activities, such as washing, bathing, and applying lotions, in acute and long-term care adult settings. The study led to a proposed 2-step program targeting adults with intact or preclinically damaged skin. [13]
Texture: Thick, hydrating gel | Ingredients: Hyaluronic acid, ceramides | Other benefits: Fragrance-free, non-comedogenic. Start your skin care routine with a gentle, hydrating facial cleanser ...
Texture: Watery | Ingredients: Water, glycerin | Other benefits: Oil-free, alcohol-free, fragrance-free | Product type: Cleanser | Problem addressed: Makeup removal for sensitive skin After ...
Brimonidine/timolol, sold under the brand name Combigan among others, is a fixed-dose combination medication eye drop used for the treatment of glaucoma. [1] It is a combination of brimonidine (an α 2 adrenergic agonist ) and timolol (a β adrenergic blocker ).
While definitive sites of metabolism have not been firmly established, there are several metabolites worthy of note. N-Desethylbrinzolamide is an active metabolite of the parent compound, and thus exhibits carbonic anhydrase inhibitory activity (largely carbonic anhydrase-I, when in the presence of Brinzolamide) and also accumulates in the erythrocytes.
Skin whitening, also known as skin lightening and skin bleaching, is the practice of using chemical substances in an attempt to lighten the skin or provide an even skin color by reducing the melanin concentration in the skin. Several chemicals have been shown to be effective in skin whitening, while some have proven to be toxic or have ...
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