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Spermiogenesis is the final stage of spermatogenesis, during which the spermatids develop into mature spermatozoa. At the beginning of the stage, the spermatid is a more or less circular cell containing a nucleus , Golgi apparatus , centriole and mitochondria ; by the end of the process, it has radically transformed into an elongated ...
The resulting spermatozoa are now mature but lack motility. The mature spermatozoa are released from the protective Sertoli cells into the lumen of the seminiferous tubule in a process called spermiation. The non-motile spermatozoa are transported to the epididymis in testicular fluid secreted by the Sertoli cells with the aid of peristaltic ...
A spermatozoon (/ s p ər ˌ m æ t ə ˈ z oʊ. ən, ˌ s p ɜːr m ə t ə-/; [1] also spelled spermatozoön; pl.: spermatozoa; from Ancient Greek σπέρμα (spérma) 'seed' and ζῷον (zôion) 'animal') is a motile sperm cell produced by male animals relying on internal fertilization.
Sperm (pl.: sperm or sperms) is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one).
It takes around 64 days to produce mature spermatozoa from differentiating SSCs, and 100 million spermatozoa can be produced each day. [22] One of the major known substances driving the differentiation of SSCs, and therefore the production of spermatozoa, is Retinoic Acid (RA). [14]
The spermatids are currently surrounded by Sertoli cells, which nourish the sperm and produce inhibin, an inhibitor of the follicle-stimulating hormone (FSH). [3] The last step of spermatogenesis is spermiogenesis. During this process, the spermatids are transformed into spermatozoa, mature sperm. At this point, no other division occurs.
Spermatozoa, in this case human, are a primary component in normal semen, and the agents of fertilization of female ova. Semen, also known as seminal fluid, is a bodily fluid that contains spermatozoa. Spermatozoa are secreted by the male gonads (sexual glands) and other sexual organs of male or hermaphroditic animals and can fertilize the ...
As postmeiotic germ cells develop to mature sperm they progressively lose the ability to repair DNA damage that may then accumulate and be transmitted to the zygote and ultimately the embryo. [5] In particular, the repair of DNA double-strand breaks by the non-homologous end joining pathway, although present in round spermatids, appears to be ...