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Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
Bupropion, formerly called amfebutamone, [16] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder, seasonal affective disorder and to support smoking cessation.
The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
Wellbutrin is the brand name for bupropion, a prescription-only antidepressant. Wellbutrin is typically sold in a tablet form that works by increasing the activity of natural chemicals called ...
Bupropion has been known to cause seizures in high therapeutic doses and in acute overdoses. For example a 16 year old ingested 1.5 g and developed seizures and cardiotoxicity. [77] There are retrospective case series with good information on dose effect relationships [78] [79] which could be used in the article.
An Oregon baby underwent surgery to remove half of his brain due to a rare disorder and seizures. Jackson Williamson was just 3 months old when he started suffering seizures. They were constant ...
Breakthrough seizures are more likely with a number of triggers. [54]: 57 Often when a breakthrough seizure occurs in a person whose seizures have always been well controlled, there is a new underlying cause to the seizure. [55] Breakthrough seizures vary. Studies have shown the rates of breakthrough seizures ranging from 11 to 37%. [56]
[14] [15] Bupropion produces nicotine-like effects in rodents and (2S,3S)-hydroxybupropion partially substitutes for nicotine. [3] In contrast, (2R,3R)-hydroxybupropion does not substitute for nicotine and dose-dependently antagonizes the effects of nicotine by up to 50%. [3] (2R,3R)-Hydroxybupropion is a strong CYP2D6 inhibitor similarly to ...