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  2. Antinuclear antibody - Wikipedia

    en.wikipedia.org/wiki/Antinuclear_antibody

    The ANA test detects the autoantibodies present in an individual's blood serum. The common tests used for detecting and quantifying ANAs are indirect immunofluorescence and enzyme-linked immunosorbent assay (ELISA). In immunofluorescence, the level of autoantibodies is reported as a titre. This is the highest dilution of the serum at which ...

  3. Anti-SSA/Ro autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-SSA/Ro_autoantibodies

    Immunofluorescence pattern of SS-A and SS-B antibodies. Produced using serum from a patient on HEp-20-10 cells with a FITC conjugate. Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA, anti–SS-A/Ro, and anti-Ro/SS-A) are a type of anti-nuclear autoantibodies that are associated with ...

  4. Anti-dsDNA antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-dsDNA_antibodies

    The levels of circulating anti-dsDNA antibodies fluctuate with disease activity in SLE. Increases in titres of the antibodies can coincide with, or even precede an increase of disease activity. For this reason titres are serially monitored by clinicians to assess disease progression.

  5. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    Autoantibody tests may be ordered as part of an investigation of chronic progressive arthritis type symptoms and/or unexplained fevers, fatigue, muscle weakness and rashes. The antinuclear antibody (ANA) test is often ordered first. ANA is a marker of the autoimmune process – it is positive with a variety of different autoimmune diseases but ...

  6. Extractable nuclear antigen - Wikipedia

    en.wikipedia.org/wiki/Extractable_nuclear_antigen

    An extractable nuclear antigen panel, or an ENA panel, tests for presence of autoantibodies in the blood that react with proteins in the cell nucleus.It is usually done as a follow-up to a positive antinuclear antibody test and when one is showing symptoms of an autoimmune disorder.

  7. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    For most substances presented, the optimal levels are the ones normally found in the population as well. More specifically, optimal levels are generally close to a central tendency of the values found in the population. However, usual and optimal levels may differ substantially, most notably among vitamins and blood lipids, so these tables give ...

  8. Anti-neutrophil cytoplasmic antibody - Wikipedia

    en.wikipedia.org/wiki/Anti-neutrophil_cytoplasm...

    Immunofluorescence (IF) on ethanol-fixed neutrophils is used to detect ANCA, although formalin-fixed neutrophils may be used to help differentiate ANCA patterns. ANCA can be divided into four patterns when visualised by IF; cytoplasmic ANCA (c-ANCA), C-ANCA (atypical), perinuclear ANCA (p-ANCA) and atypical ANCA (a-ANCA), also known as x-ANCA. c-ANCA shows cytoplasmic granular fluorescence ...

  9. Anti-topoisomerase antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-topoisomerase_antibodies

    Since this activity occurs in the nucleus of the cell ATA is a form of antinuclear antibody. Scleroderma results from the overproduction of collagen in affected tissues, one study claims that there is an increased density of Topoisomerase I sites in the collagen genes, and that the antibodies may be altering transcription at these loci. [7]

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