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Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural demyelinating lesion; and is more common in children. [56] [57] Solitary sclerosis: This variant was proposed (2012) by Mayo Clinic researchers. [58] though it was also reported by other groups more or less at the same time.
Fallout 76 is a narrative prequel to previous Fallout games. It is set in an alternate history , [ 18 ] and takes place in 2102, twenty-five years after a nuclear war that devastated the Earth. The player character is a resident of Vault 76, a fallout shelter that was built in West Virginia to house America's best and brightest minds.
“Fallout 76” has found a whole new world of players thanks to the popularity of Amazon’s “Fallout” TV series. The Bethesda Game Studios title, which first launched in October 2018 ...
Functional weakness is weakness of an arm or leg without evidence of damage or a disease of the nervous system. Patients with functional weakness experience symptoms of limb weakness which can be disabling and frightening such as problems walking or a 'heaviness' down one side, dropping things or a feeling that a limb just doesn't feel normal or 'part of them'.
Symptoms of functional neurological disorders are clinically recognisable, but are not categorically associated with a definable organic disease. [ 1 ] [ 2 ] The intended contrast is with an organic brain syndrome , where a pathology (disease process) which affects the body's physiology can be identified.
Complex regional pain syndrome is a multifactorial disorder with clinical features of neurogenic inflammation (inflammation mediated by nerve cells), nociceptive sensitisation (which causes extreme sensitivity or allodynia), vasomotor dysfunction (blood flow problems which cause swelling and discolouration) and maladaptive neuroplasticity ...
Symptoms may include difficulty with balance, weakness and stiffness in the legs, and clumsiness. Other common symptoms are spasticity (involuntary muscle contraction due to the stretching of muscle, which depends on the velocity of the stretch) in the hands, feet, or legs, foot dragging , and speech and swallowing problems due to involvement ...
Neuromyelitis optica (NMO) is a particular disease within the NMOSD spectrum. It is characterised by optic neuritis and longitudinally extensive myelitis. In more than 80% of NMO cases, the cause is immunoglobulin G autoantibodies to aquaporin 4 , the most abundant water channel protein in the central nervous system. [5] [1] [4]