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The middle cerebellar peduncle is the largest of the three cerebellar peduncles. It connects the pons and cerebellum.It consists almost entirely of fibers passing from the pons to the cerebellum (fibrocerebellar fibers); the fibers arise from the pontine nuclei and decussate within the pons before entering the peduncle [1] to end in the contralateral cerebellar hemisphere.
The cerebellar peduncles are three paired bundles of fibres that connect the cerebellum to the brain stem. [1] Superior cerebellar peduncle is a paired structure of white matter that connects the cerebellum to the mid-brain. Middle cerebellar peduncles connect the cerebellum to the pons and are composed entirely of centripetal fibers.
Pontocerebellar fibers are the sole efferent pathway of the pontine nuclei. The fibers mostly decussate within the pons to pass through the (contralateral) middle cerebellar peduncle to terminate in the contralateral cerebellum as mossy fibers; they form terminal synapses in the cerebellar cortex, but also issue collaterals to the cerebellar nuclei.
The middle peduncle is the largest of the three and its afferent fibers are grouped into three separate fascicles taking their inputs to different parts of the cerebellum. The inferior cerebellar peduncle receives input from afferent fibers from the vestibular nuclei, spinal cord and the tegmentum.
The entire pathway begins and ends in the cerebral cortex, and its entire course is the following: [2] (Motor and sensory areas of) cerebral cortex → corticopontine fibers → (ipsilateral) nuclei pontis (synapse) → pontocerebellar fibers (decussation within pons) → middle cerebellar peduncle → (contralateral) (cerebellar cortex and (collaterals) dentate nucleus of) posterior lobe of ...
In medicine, a mass such as a cyst or polyp is said to be pedunculated if it is supported by a peduncle. [2] There are in total three types of peduncles in the cerebellum of the human brain, known as superior cerebellar peduncle, middle cerebellar peduncle, and inferior cerebellar peduncle. [3]
The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons.
Cerebral peduncle. Crus cerebri; Mesencephalic cranial nerve nuclei. Oculomotor nucleus (III) Edinger-Westphal nucleus; Trochlear nucleus (IV) Mesencephalic duct (cerebral aqueduct, aqueduct of Sylvius)