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A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...
The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.
Three interlocking revolutions had, he argued, taken place in evolutionary biology: molecular, microbiological, and genomic. The molecular revolution included the neutral theory, that most mutations are neutral and that negative selection happens more often than the positive form, and that all current life evolved from a single common ancestor.
Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...
The neutral theory of molecular evolution, proposed by Motoo Kimura in 1968, holds that at the molecular level most evolutionary changes and most of the variation within and between species is not caused by natural selection but by genetic drift of mutant alleles that are neutral.
Neutral theory – Theory of evolution by changes at the molecular level; Shifting balance theory – One version of the theory of evolution; Price equation – Description of how a trait or gene changes in frequency over time; Coefficient of relationship – Mathematical guess about inbreeding; Fitness – Expected reproductive success
Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution.
According to Ohta, however, the nearly neutral theory largely fell out of favor in the late 1980s, because of the mathematically simpler neutral theory for the widespread molecular systematics research that flourished after the advent of rapid DNA sequencing. As more detailed systematics studies started to compare the evolution of genome ...