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Acetazolamide is a first generation carbonic anhydrase inhibitor and it decreases the ocular fluid and osmolality in the eye to decrease intraocular pressure. [5] [6] Common side effects include numbness, ringing in the ears, loss of appetite, vomiting, and sleepiness. [2]
An undesirable side-effect of acetazolamide is a reduction in aerobic endurance performance. Other minor side effects include a tingle-sensation in hands and feet. Although a sulfonamide, acetazolamide is a non-antibiotic and has not been shown to cause life-threatening allergic cross-reactivity in those with a self-reported sulfonamide allergy.
Acetazolamide is an inhibitor of carbonic anhydrase. It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
Ethotoin is available in 250 mg tablets. [3] [4] ... Side effects. Side effects include ataxia, visual disturbances, rash, and gastrointestinal problems.
Severe side effects may include suicide and psychosis. [ 8 ] [ 7 ] Use during pregnancy may result in harm to the fetus. [ 9 ] Primidone is an anticonvulsant of the barbiturate class; [ 7 ] however, its long-term effect in raising the seizure threshold is likely due to its active metabolite, phenobarbital . [ 10 ]
Ocular stinging, burning, itching and bitter taste. [8] It causes shallowing of the anterior chamber and leads to transient myopia.As a second generation carbonic anhydrase inhibitor, dorzolamide avoids systemic effects associated with first generation carbonic anhydrase inhibitors such as acetazolamide, methazolamide, and dichlorphenamide.
This drug has displayed teratogenic effects in rats. Compared to another drug in the same class, acetazolamide, methazolamide requires a lower dose when administered to patients. Recently, research has also uncovered a potential new role for this drug, addressing tau toxicity, a theorized cause for diseases such as Alzheimer’s. [1]
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related to: acetazolamide 250 mg side effectsgoodrx.com has been visited by 100K+ users in the past month
109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"About 50% of US physicians advise patients consult GoodRx." - Fortune