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List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...
Most of the antiviral drugs now available are designed to help deal with HIV, herpes viruses, the hepatitis B and C viruses, and influenza A and B viruses. [ 6 ] Viruses use the host's cells to replicate and this makes it difficult to find targets for the drug that would interfere with the virus without also harming the host organism's cells.
Ribavirin is primarily used to treat chronic hepatitis C and viral hemorrhagic fevers (an orphan indication in most countries). [11] Its efficacy for these purposes has been questioned in light of its Food and Drug Administration boxed warning against its use as monotherapy for chronic hepatitis C.
In Columbus, Ohio, a teenage boy who was undergoing treatment for substance use disorder was surprised a couple years ago to learn he'd been infected with hepatitis C. The boy, then 17, was ...
There is no vaccine against hepatitis C. [1] [9] Prevention includes harm reduction efforts among people who inject drugs, testing donated blood, and treatment of people with chronic infection. [4] [10] Chronic infection can be cured more than 95% of the time with antiviral medications such as sofosbuvir or simeprevir.
What was once a dire diagnosis is now a lot more hopeful.
Likely, vaccines following the first approved vaccine will address other genotypes by prevalence. VLP-based HCV vaccines are also subject of intensive research. [6] Since 2014, well-tolerated and extremely effective direct‐acting antiviral agents (DAAs) have been available which allows eradication of the disease in 8–12 weeks in most ...
Elbasvir/grazoprevir, sold under the brand name Zepatier, is a fixed-dose combination for the treatment of hepatitis C, containing elbasvir (an inhibitor of hepatitis C virus's NS5A protein) and grazoprevir (an NS3/4A inhibitor). It is used to treat chronic hepatitis C virus (HCV) genotypes 1 or 4 infection in both treatment-naïve and ...
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