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Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
Aside from making healthy lifestyle improvements, Dr. Kumar says that PCOS is often treated with a variety of medications, including metformin, hormonal contraception, and spironolactone. You ...
There is no specific antidote for overdose of spironolactone. [8] Treatment may consist of induction of vomiting or stomach evacuation by gastric lavage. [8] The treatment of spironolactone overdose is supportive, with the purpose of maintaining hydration, electrolyte balance, and vital functions. [8]
Spironolactone. Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS.
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Spironolactone is a prodrug with a short terminal half-life of 1.4 hours. [5] [6] [7] The active metabolites of spironolactone have extended terminal half-lives of 13.8 hours for 7α-TMS, 15.0 hours for 6β-OH-7α-TMS, and 16.5 hours for canrenone, and accordingly, these metabolites are responsible for the therapeutic effects of the drug. [5] [6]
PCOS is a common reason why women have difficulty getting pregnant. Here are the symptoms to look out for. ... leading to fragmented and disjointed medical advice and treatment," she says ...
For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the anovulation is the principal treatment used to help infertility in PCOS. Letrozole and Clomiphene citrate are the first-line treatment in subfertile anovulatory patients with PCOS. [12]