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Brush border cells are found mainly in the following organs: The small intestine tract: This is where absorption takes place. [2] [3] [4] The brush borders of the intestinal lining are the site of terminal carbohydrate digestions. The microvilli that constitute the brush border have enzymes for this final part of digestion anchored into their ...
Thousands of microvilli form a structure called the brush border that is found on the apical surface of some epithelial cells, such as the small intestines. (Microvilli should not be confused with intestinal villi, which are made of many cells. Each of these cells has many microvilli.)
Brachyspira pilosicoli is a gram-negative, anaerobic, host-associated spirochete that colonizes the intestinal tract of animals and humans. [2] [3] It appears as a characteristic "false brush border" due to its end-on attachment to enterocytes of the colon where it interferes with intestinal absorption. [4]
Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine.Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border.
Polysaccharidases and disaccharidases in the glycocalyx break down large sugar molecules, which are then absorbed. Glucose crosses the apical membrane of the enterocyte using the sodium-glucose cotransporter. It moves through the cytosol (cytoplasm) and exits the enterocyte via the basolateral membrane (into the blood capillary) using GLUT2.
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The microvilli create a brush border that increases the area for absorption. In the ileum there are occasionally Peyer's patches in the lamina propria. Brunner's glands are found in the duodenum but not in other parts of the small intestine. [1] In the colon, epithelium is simple columnar and without villi.
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