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Hexagonal cells of corneal endothelium visualized by specular microscopy. The principal physiological function of the corneal endothelium is to allow leakage of solutes and nutrients from the aqueous humor to the more superficial layers of the cornea while at the same time pumping water in the opposite direction, from the stroma to the aqueous.
David Myer Maurice (3 April 1922 in London – 20 July 2002 in Manhattan) was a British ophthalmologist, noted for his contributions to the development of the specular microscope used for examination of the cornea. [1] [2]
Scheimpflug imaging, anterior segment optical coherence tomography, confocal microscopy, and specular microscopy are additional imaging techniques that can identify the presence of guttae and quantify the thickness of the cornea. While corneal thickness can be a valuable indicator of how the cornea is changing over time, it is affected by ...
Long-term contact lens use can lead to alterations in corneal thickness, stromal thickness, curvature, corneal sensitivity, cell density, and epithelial oxygen uptake. . Other structural changes may include the formation of epithelial vacuoles and microcysts (containing cellular debris), corneal neovascularization, as well as the emergence of polymegethism in the corneal endoth
Eye examination with the aid of a slit lamp. Side view of a slit lamp machine. Cataract in human eye: magnified view seen on examination with the slit lamp. In ophthalmology and optometry, a slit lamp is an instrument consisting of a high-intensity light source that can be focused to shine a thin sheet of light into the eye.
Copper disposition on corneal Descemet's membrane. Significant damage to the membrane may require a corneal transplant. Damage caused by the hereditary condition known as Fuchs dystrophy (q.v.)—where Descemet's membrane progressively fails and the cornea thickens and clouds because the exchange of nutrients/fluids between the cornea and the rest of the eye is interrupted—can be reversed by ...
Corneal pachymetry is the process of measuring the thickness of the cornea.A pachymeter is a medical device used to measure the thickness of the eye's cornea.It is used to perform corneal pachymetry prior to refractive surgery, for Keratoconus screening, LRI surgery [1] and is useful in screening for patients suspected of developing glaucoma among other uses.
At least four Purkinje images are usually visible in the normal eye. The first Purkinje image (P1) is the reflection from the outer surface of the cornea. The second Purkinje image (P2) is the reflection from the inner surface of the cornea. The third Purkinje image (P3) is the reflection from the outer (anterior) surface of the lens. The ...