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This 'globin fold' typically consists of eight alpha helices, although some proteins have additional helix extensions at their termini. [4] Since the globin fold contains only helices, it is classified as an all-alpha protein fold. The globin fold is found in its namesake globin families as well as in phycocyanins. The globin fold was thus the ...
Schematic representation of a protein electrophoresis gel. All globulins fall into one of three categories: Alpha globulins; Beta globulins; Gamma globulins (one group of gamma globulins is the immunoglobulins, which are also known as "antibodies")
Among the most known globular proteins is hemoglobin, a member of the globin protein family. Other globular proteins are the alpha , beta and gamma (IgA, IgD, IgE, IgG and IgM) globulin. See protein electrophoresis for more information on the different globulins.
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n/a Ensembl ENSG00000223609 n/a UniProt P02042 n/a RefSeq (mRNA) NM_000519 n/a RefSeq (protein) NP_000510 n/a Location (UCSC) Chr 11: 5.23 – 5.24 Mb n/a PubMed search n/a Wikidata View/Edit Human Hemoglobin subunit delta is a protein that in humans is encoded by the HBD gene. Function The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta ...
544763 Ensembl ENSG00000086506 ENSMUSG00000073063 UniProt P09105 Q3U0A6 RefSeq (mRNA) NM_005331 NM_001033981 RefSeq (protein) NP_005322 NP_001029153 Location (UCSC) Chr 16: 0.18 – 0.18 Mb Chr 11: 32.24 – 32.24 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is found in human ...
Beta-globin is produced by the gene HBB which is located in the multigene locus of β-globin locus on chromosome 11, specifically on the short arm position 15.4. Expression of beta globin and the neighbouring globins in the β-globin locus is controlled by single locus control region (LCR), the most important regulatory element in the locus located upstream of the globin genes. [9]
15132 Ensembl ENSG00000213931 ENSMUSG00000052217 UniProt P02100 P04444 RefSeq (mRNA) NM_005330 NM_008219 RefSeq (protein) NP_005321 NP_005321.1 NP_032245 Location (UCSC) Chr 11: 5.27 – 5.51 Mb Chr 7: 103.49 – 103.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hemoglobin subunit epsilon is a protein that in humans is encoded by the HBE1 gene. Function The epsilon globin gene ...