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Research has shown that non-SNP variation accounts for more human genetic variation than single nucleotide diversity. Structural variation includes copy-number variation and results from deletions, inversions, insertions and duplications. It is estimated that approximately 0.4 to 0.6 percent of the genomes of unrelated people differ.
In it, Lewontin presented an analysis of genetic diversity amongst people from different conventionally-defined races. His main finding, that there is more genetic variation within these populations than between them, [2] is considered a landmark in the study of human genetic variation and contributed to the abandonment of race as a scientific ...
The lack of discontinuities in genetic distances between human populations, absence of discrete branches in the human species, and striking homogeneity of human beings globally, imply that there is no scientific basis for inferring races or subspecies in humans, and for most traits, there is much more variation within populations than between them.
"Human Genetic Diversity: Lewontin's Fallacy" is a 2003 paper by A. W. F. Edwards in the journal BioEssays. [1] He criticises an argument first made in Richard Lewontin's 1972 article "The Apportionment of Human Diversity", that the practice of dividing humanity into races is taxonomically invalid because any given individual will often have more in common genetically with members of other ...
A 2002 study found that about 13% of human craniometric variation existed between regions, while 6% existed between local populations within regions and 81% within local populations. In contrast, the opposite pattern of genetic variation was observed for skin color (which is often used to define race), with 88% of variation between regions.
A wide range of methods have been developed to assess the structure of human populations with the use of genetic data. Early studies of within and between-group genetic variation used physical phenotypes and blood groups, with modern genetic studies using genetic markers such as Alu sequences, short tandem repeat polymorphisms, and single nucleotide polymorphisms (SNPs), among others. [14]
The Human Genome Diversity Project (HGDP) was started by Stanford University's Morrison Institute in 1990s along with collaboration of scientists around the world. [1] It is the result of many years of work by Luigi Cavalli-Sforza, one of the most cited scientists in the world, who has published extensively in the use of genetics to understand human migration and evolution.
The finding that "Mitochondrial Eve" was relatively recent and African seemed to give the upper hand to the proponents of the Out of Africa hypothesis.But in 2002, Alan Templeton published a genetic analysis involving other loci in the genome as well, and this showed that some variants that are present in modern populations existed already in Asia hundreds of thousands of years ago. [31]