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Today, pen needles are manufactured at shorter needle lengths than required for typical vial and syringe administration, which decreases the pain associated with injection. [2] They are available in multiple lengths and gauge of needle , including 3.5mm, 4mm, 5mm, and 8mm lengths, and 31 through 34 gauge. [ 8 ]
Needles in common medical use range from 7 gauge (the largest) to 34 (the smallest). 21-gauge needles are most commonly used for drawing blood for testing purposes, and 16- or 17-gauge needles are most commonly used for blood donation, as the larger luminal cross-sectional area results in lower fluid shear, reducing harm to red blood cells ...
Microneedles (MNs) consist of micro-sized needles arrays that are made of various materials exhibiting different characteristics and are suitable in the synthesis of different types of MNs. The selection of materials for formation of MNs greatly depends on the strength of skin penetration, manufacturing method, and rate of drug release.
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The Birmingham gauge ranges from 5/0 or 00000, the lowest gauge number corresponding to the largest size of 0.500 inches (12.7 mm), to 36, the highest gauge number corresponding to the smallest size of 0.004 inches (0.10 mm).
[4] [12] Polypropylene is used instead of polystyrene because it absorbs impact better, reducing the chance of the pen cracking or splitting if it is dropped onto the cap. [13] The pen's dimensions are 5 + 7 ⁄ 8 by 1 ⁄ 2 inch (14.9 cm × 1.3 cm) with the cap, [11] or 14.5 cm × 0.7 cm (5 + 11 ⁄ 16 in × 1 ⁄ 4 in) without the cap.
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