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A cell during anaphase. Microtubules are visible in green. Stages of late M phase in a vertebrate cell. Anaphase (from Ancient Greek ἀνα-() 'back, backward' and φάσις (phásis) 'appearance') is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell.
Cytological markers of BFB-cycle-mediated chromosomal instability: "budding" nuclei (A, C, D) and partly fragmented nucleus with double nucleoplasmic bridge (B). [ 1 ] Breakage-fusion-bridge (BFB) cycle (also breakage-rejoining-bridge cycle ) is a mechanism of chromosomal instability , discovered by Barbara McClintock in the late 1930s.
The anaphase-promoting complex (APC) is a large protein complex containing 11–13 subunits, including a RING subunit (Apc11) and a cullin (Apc2). APC activity requires association with activator subunits (Cdc20 or Cdh1) that contribute to substrate binding.
Progression from metaphase to anaphase is marked by sister chromatid separation. The cell cycle surveillance mechanism that prevents sister-chromatid separation and transition into anaphase is called the spindle checkpoint. As a safeguard against chromosome segregation errors, the spindle assembly checkpoint (SAC) delays anaphase until all ...
The U.S. Department of Energy has zeroed in on three regions of the country it has determined are in major need of new electric transmission infrastructure and eligible for future federal funding ...
The breaking of the mitotic spindle, common to the completion of mitosis in all eukaryotes, is the event most often used to define the anaphase-B to telophase transition, [2] [6] although the initiation of nuclear reassembly tends to precede that of spindle disassembly. [11]
Three Boar's Head deli meat plants were cited for unsanitary conditions, including insects, mold, and "unidentified slime," according to newly released federal records.
Kansas City Chiefs star Travis Kelce told fans on Friday what playoff football meant to him ahead of their AFC Divisional Round matchup against the Houston Texans.. The message came as Kelce spoke ...