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Peripheral Arterial Tone (PAT) is a noninvasive measure designed to track pulsatile volume changes in peripheral arterial beds. The collected information gives specialists important insight into the autonomic nervous system and the cardiovascular system .
Bayliss effect or Bayliss myogenic response is a special manifestation of the myogenic tone in the vasculature. [3] [4] The Bayliss effect in vascular smooth muscles cells is a response to stretch. This is especially relevant in arterioles of the body. When blood pressure is increased in the blood vessels and the blood vessels distend, they ...
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system. The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance , while the resistance caused by the pulmonary circulation is known ...
First, metabolites that are produced by active muscle use can alter skeletal muscle tone. Second, skeletal muscle can undergo hyperemia, which is a mechanism of local blood flow regulation with two major subtypes. Regardless of the subtype, the result of hyperemia is an increase in blood flow to the affected skeletal muscle. [4]
Moreover, impaired blood flow resulting from abnormal vasoconstriction may contribute to tissue ischemia, which can be observed in conditions like Raynaud's disease. Understanding the pathology of vasoconstriction is crucial for developing targeted therapeutic strategies to manage conditions associated with abnormal vascular tone. [17]
Endothelin-1 is the most powerful endogenous chemical affecting vascular tone across organ systems. [2] [13] Secretion of endothelin-1 from the vascular endothelium signals vasoconstriction and influences local cellular growth and survival. [13]
This reduces sympathetic tone to vascular smooth muscle. [9] This reduces heart rate and vascular resistance. [9] Digoxin increases vagal tone from the vasomotor centre, which decreases pulse. [7] G-series nerve agents have their most potent effect in the vasomotor center. [10]
It can be used to demonstrate effects of drugs on the venous tone while the circulating blood volume remains constant, [5] or to measure haemodynamic changes during haemorrhage. [ 6 ] Mean systemic pressure increases if there is an increase in blood volume or if there is a decrease in venous compliance (where blood is shifted from the veins to ...
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