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A low-FODMAP diet is a person's global restriction of consumption of all fermentable carbohydrates (), [1] recommended only for a short time. A low-FODMAP diet is recommended for managing patients with irritable bowel syndrome (IBS) and can reduce digestive symptoms of IBS including bloating and flatulence.
IBS/IBD individuals are less often HLA DQ2/8 positive than in upper functional gastrointestinal disease and healthy populations. [198] Efficacy of mast cell directed therapies in irritable bowel syndrome is an area of ongoing research. [199]
Iberogast, also known as STW5, is a liquid formulation of nine herbs used for functional dyspepsia and irritable bowel syndrome.A proprietary blend, it was developed in Germany in 1961 and is available (without prescription) in other countries.
In humans, oral immunoglobulins may improve function in the gastrointestinal (GI) tract. [6] Conditions like HIV-enteropathy, IBS-D (irritable bowel syndrome with diarrhea), SIBO (small intestine bacterial overgrowth), recurrent C. difficile infection-associated diarrhea and post-infectious IBS-D often limit or impair the body's ability to absorb and digest select nutrients including water. [5]
More study is needed to evaluate its effectiveness in children with irritable bowel syndrome. [8] Small studies (which are susceptible to bias) show little evidence of its effectiveness in treating functional symptoms of inflammatory bowel disease (IBD). [31] [32] More study is needed to assess the true impact of this diet on health. [9] [11]
In a review of 18 studies of the use of SeHCAT testing in diarrhea-predominant irritable bowel syndrome patients, 32% of 1223 people had a SeHCAT 7-day retention of less than 10%, and 80% of these reported a response to cholestyramine, a bile acid sequestrant. [16]
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