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Hippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus. [1] Neuroimaging tests such as magnetic resonance imaging (MRI) and positron emission tomography (PET) may identify individuals with hippocampal sclerosis. [ 2 ]
They most commonly arise from the mesial temporal lobe, particularly the amygdala, hippocampus, and neocortical regions. [17] A common associated brain abnormality is mesial temporal sclerosis. [15] Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy. [18]
Temporal lobe epilepsy is the most common focal onset epilepsy, and 80% of temporal lobe epilepsy is mesial (medial) temporal lobe epilepsy, temporal lobe epilepsy arising from the inner part of the temporal lobe that may involve the hippocampus, parahippocampal gyrus or amygdala.
His work has focused on establishing the electrophysiologic and neuroimaging endophenotypes of TBI. His group showed that mesial temporal sclerosis was a common finding in post-traumatic epilepsy of adult onset. [10] He published a study of post-traumatic epilepsy evaluated with MRI and video-EEG monitoring over 10 years at a single epilepsy ...
Mesial temporal sclerosis, pattern of hippocampal neuron cell loss; Mohr–Tranebjærg syndrome, also known as deafness–dystonia syndrome; MTS assay, a biochemical cell assay used in research; Muir–Torre syndrome, a cancer syndrome
Temporal lobe epilepsy (TLE) is not a classic syndrome but mentioned here because it is the most common epilepsy of adults. It is a symptomatic localization-related epilepsy and in most cases the epileptogenic region is found in the midline ( mesial ) temporal structures (e.g., the hippocampus , amygdala , and parahippocampal gyrus ).
Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...
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