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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Besides pain at the ulcer site and local tissue destruction (which may be severe), individuals with EBV+ mucocutaneous ulcer are symptomless and lack lymphadenopathy (i.e. enlarged and painful lymph nodes), involvement in other tissues, or B symptoms. However, ulcers in the gastrointestinal tract may present with a variety of abdominal symptoms ...
Lower left abdominal pain can have many causes, ranging from minor to serious, says Andrew Boxer, M.D., gastroenterologist of Gastroenterology Associates of New Jersey. Common causes include:
Abdominal pain is one of the top reasons people seek medical treatment—and no wonder: It could be anything from a pulled muscle to a life-threatening aneurysm. Check out the 10 types of pain you ...
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
Castell's has been shown to be superior in sensitivity to other spleen percussion signs as well as palpation, which is not likely useful due to the extreme enlargement necessary to feel the spleen below the costal margin. Castell's sign is thus, in the appropriate clinical scenario, an important part of the abdominal physical exam. [5]
In 1967, a technician in their laboratory developed mononucleosis and they were able to compare a stored serum sample, showing that antibodies to the virus developed. [ 77 ] [ 79 ] [ 80 ] In 1968, they discovered that EBV can directly immortalize B cells after infection, [ 43 ] mimicking some forms of EBV-related infections, [ 78 ] and ...