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2. Benadryl for Dogs? A Vet Explains How Much You Should Give - AOL

   www.aol.com/benadryl-dogs-vet-explains-much...

   The standard dose is about the same, 1–2 mg per pound of body weight, but a slightly higher dose of 3 mg per pound may be helpful with some dogs. (This is higher than the dose recommended, but ...

3. Direct factor Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

   A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15] In 1987, Tuszynski et al. discovered antistasin, which was isolated from the extracts of the Mexican leech, Haementeria officinalis.

4. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Use is not recommended during pregnancy or breastfeeding. [1] [7] Use appears to be relatively safe in those with mild kidney problems. [7] Compared to warfarin it has fewer interactions with other medications. [10] It is a direct factor Xa inhibitor. [6] In 2007, Pfizer and Bristol-Myers Squibb began the development of apixaban as an ...

5. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   In dog testing, this compound with a carboxamide group called 13F, showed a great pharmacokinetical profile, a low clearance and adequate half-life and volume of distribution. Due to the success of finding a stabilizing group, SAR research for S1 binding moiety (p-methoxyphenyl) was discontinued.

6. 7 Alternatives to Chemotherapy for Lymphoma in Dogs - AOL

   www.aol.com/7-alternatives-chemotherapy-lymphoma...

   1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...

7. Skin conditions in dogs: Symptoms, causes, and how to help - AOL

   www.aol.com/skin-conditions-dogs-symptoms-causes...

   The dog then causes further trauma to the skin by itching and rubbing at the area, leading to a secondary bacterial infection." Acute moist dermatitis: Symptoms A patch of moist, inflamed skin ...