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Streptomyces lydicus is a bacterium species from the genus of Streptomyces which has been isolated from soil in the United States. [1] [2] ...
The following is a list of Streptomyces species, organized alphabetically by species name. [1] Names that have not been validated according to the Bacteriological Code are enclosed in "quotes". As of June 2021 [update] , there are 679 valid species of Streptomyces and an additional 121 provisional species. [ 1 ]
Streptomyces is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. [3] Over 700 species of Streptomyces bacteria have been described. [ 4 ] [ 5 ] [ 6 ] As with the other Actinomycetota, streptomycetes are gram-positive , and have very large genomes with high GC content .
Streptomyces isolates have yielded the majority of human, animal, and agricultural antibiotics, as well as a number of fundamental chemotherapy medicines.Streptomyces is the largest antibiotic-producing genus of Actinomycetota, producing chemotherapy, antibacterial, antifungal, antiparasitic drugs, and immunosuppressants. [1]
Migalastat was isolated as a fermentation product of the bacterium Streptomyces lydicus (strain PA-5726) in 1988 and called 1-deoxygalactonojirimycin. [15] [16] In 2004, it was designated orphan drug status by the US FDA for the treatment of Fabry disease, [5] and in 2006 the European CHMP did likewise. [17]
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