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The insular cortex is divided by the central sulcus of the insula, into two parts: the anterior insula and the posterior insula in which more than a dozen field areas have been identified. The cortical area overlying the insula toward the lateral surface of the brain is the operculum (meaning lid ).
The salience network is theorized to mediate switching between the default mode network and central executive network. [1] [2]The salience network (SN), also known anatomically as the midcingulo-insular network (M-CIN) or ventral attention network, is a large scale network of the human brain that is primarily composed of the anterior insula (AI) and dorsal anterior cingulate cortex (dACC).
The islands of Calleja are specifically located within the ventral and medial lining of the ventral striatum in the brain, meaning that they lie towards the front and middle of this region within the temporal lobe. The insula magna, or the major island, of these complexes is located in the medial border of the nucleus accumbens.
The insula is considered to be a "hub" region because it has an extremely high number of connections with other brain areas, suggesting it may be important for an integration of lower-level physiological information and salience. [52] The insula connects to many regions in the brain and is highly involved in many homeostatic functions.
Normally, the insular opercula begin to develop between the 20th and the 22nd weeks of pregnancy. At weeks 14 to 16 of fetal development, the insula begins to invaginate from the surface of the immature cerebrum of the brain, until at full term, the opercula completely cover the insula. [4] This process is called opercularization. [5]
The claustrum is a small bilateral gray matter structure (comprising roughly 0.25% of the cerebral cortex) located deep to the insular cortex and extreme capsule, and superficial to the external capsule and basal ganglia.
Network neuroscience is an approach to understanding the structure and function of the human brain through an approach of network science, through the paradigm of graph theory. [1] A network is a connection of many brain regions that interact with each other to give rise to a particular function. [ 2 ]
Area 15, like all Brodmann areas, is defined on the basis of cytoarchitecture of the region of cortex. The cortex in area 15 is thinner than in the rest of the insula and temporal lobe.
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