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Until 2006, NyQuil Cold/Flu Multisymptom Relief and NyQuil Sinus contained pseudoephedrine (30 mg/15 mL), a nasal decongestant that also formed the active ingredient in Sudafed. Following the passage of the Combat Methamphetamine Epidemic Act in 2006, in the United States all pseudoephedrine-containing medications must be kept behind a pharmacy ...
[24] [2] [25] [1] As such, it is an indirectly acting sympathomimetic. [24] [2] [25] [1] Pseudoephedrine significantly crosses into the brain, but has some peripheral selectivity due to its hydrophilicity. [25] [26] Chemically, pseudoephedrine is a substituted amphetamine and is closely related to ephedrine, phenylpropanolamine, and amphetamine.
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a ...
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A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness).
The mean elimination half-life of levmetamfetamine ranges between 10.2 and 15.0 hours. [2] [4] For comparison, the elimination half-life of dextromethamphetamine was around 10.2 to 10.7 hours in the same studies. [2] [4] The clearance of levmetamfetamine is 15.5 to 19.1 L/h or 0.221 L/h⋅kg. [2] [4] [3]
Some brand names include: Benylin, Sudafed, Robitussin and Vicks among others. [35] Most contain a number of active ingredients. [4] The Thai company Hatakabb produces the Takabb Anti-Cough Pill, which is a Chinese herbal medication. [36] Sudafed is a brand manufactured by McNeil Laboratories.
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...