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Gallium (68 Ga) gozetotide or Gallium (68 Ga) PSMA-11 sold under the brand name Illuccix among others, is a radiopharmaceutical made of 68 Ga conjugated to prostate-specific membrane antigen (PSMA) targeting ligand, Glu-Urea-Lys(Ahx)-HBED-CC, used for imaging prostate cancer by positron emission tomography (PET). [10]
[69] 4) Butyric acid inhibited the proliferation of and triggered apoptosis in cultured human A549 lung cancer cells; [70] further studies in A549 as well as H1299 human lung cancer cells found that propionic acid inhibited their stimulated migration, invasiveness, and colony growth in cell culture assays but did not do so in FFAR2 gene ...
Propionate fermentation is a form of fermentation with propionic acid as one of the products. This process is done through the fermentation pathway of bacteria. It is used in a variety of industrial, food-making, and medical applications.
Propionic acid inhibits the growth of mold and some bacteria at levels between 0.1 and 1% by weight. As a result, some propionic acid produced is consumed as a preservative for both animal feed and food for human consumption. For animal feed, it is used either directly or as its ammonium salt. This application accounts for about half of the ...
δ-Aminolevulinic acid (also dALA, δ-ALA, 5ALA or 5-aminolevulinic acid), an endogenous non-proteinogenic amino acid, is the first compound in the porphyrin synthesis pathway, the pathway that leads to heme [3] in mammals, as well as chlorophyll [4] in plants. 5ALA is used in photodynamic detection and surgery of cancer. [5] [6] [7] [8]
GPR84 binds and is activated by medium-chain fatty acids consisting of 9 to 14 carbon atoms such as capric, undecaenoic, and lauric acids. [21] [22] It has been recognized as a possible member of the free fatty acid receptor family in some publications [23] but has not yet been given this designation perhaps because these medium-chain fatty acid activators require very high concentrations (e.g ...
The study also found that the offspring of mothers who drank propionic acid-laced water had fewer eosinophils and T helper cells in their airways than the offsprings of mothers who drank pure water, acetic acid-laced water, or butyric acid-laced water. Propionic acid-laced water did not suppress the development of asthma in Ffar3 gene knockout ...
These studies revealed the role of the p75NTR as a tumor suppressor [12] in prostate epithelial cells and that loss of p75NTR mRNA stability in tumor cells contributes to malignant transformation of normal cells to a cancer phenotype. [13] Moreover, treatment of tumor cells with selective non-steroidal anti-inflammatory drugs (NSAIDs) was shown ...