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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
Associations of PPI use and cardiovascular events have also been widely studied but clear conclusions have not been made as these relative risks are confounded by other factors. [ 55 ] [ 56 ] PPIs are commonly used in people with cardiovascular disease for gastric protection when aspirin is given for its antiplatelet actions.
The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion. The anti-ulcer dosing regimens generally repair the injury of gastric mucosal layer in PUD. Examples of dosing regimen: [17] Amoxicillin + clarithromycin + PPI; Bismuth subsalicylate + tetracycline + metronidazole + PPI
According to Cleveland, you should also avoid taking NSAIDs if you are pregnant, or have a history of stroke or heart attack, heart failure, stomach ulcers, Crohn’s disease or ulcerative colitis ...
In a study with patients living with type 2 diabetes, patients were randomized to take Ozempic 0.5 mg, 1.0 mg weekly, or a placebo. ... The indications for diabetes management are similar for both ...
Pantoprazole was first prepared in April 1985 by a small group of scale-up chemists. It is a dimethoxy-substituted pyridine bound to a fluoroalkoxy substituted benzimidazole. [5] Pantoprazole sodium is available as gastroresistant or delayed release tablets and as lyophilized powder for intravenous use.
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Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]