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Latanoprost was approved for medical use in the United States and the European Union in 1996. [5] [3] It is on the World Health Organization's List of Essential Medicines. [7] Latanoprost is available as a generic medication. [8] In 2022, it was the 67th most commonly prescribed medication in the United States, with more than 9 million ...
Netarsudil/latanoprost, sold under the brand name Rocklatan among others, is a fixed-dose combination medication use to treat elevated intraocular pressure (IOP) in people with open-angle glaucoma or ocular hypertension. [1] [2] It contains netarsudil mesylate and latanoprost. [1] [2] It is applied as eye drops to the eyes. [1] [2]
Ifosfamide is a DNA-damaging alkylating agent, belonging to the same class of chemotherapy drugs as cyclophosphamide. It is a prodrug, meaning that It has to be converted by CYP450 into its main active metabolites-(Iso)phosphoramide mustards. These metabolites form DNA cross links mainly at Guanine N-7 positions. [5]
Calcipotriol, also known as calcipotriene, is a synthetic derivative of calcitriol, a form of vitamin D.It is used in the treatment of psoriasis. [1] It is safe for long-term application in psoriatic skin conditions.
In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues.
Anticoagulants are defined as chronic (death occurs one to two weeks after ingestion of the lethal dose, rarely sooner), single-dose (second generation) or multiple-dose (first generation) rodenticides, acting by effective blocking of the vitamin-K cycle, resulting in inability to produce essential blood-clotting factors—mainly coagulation factors II (prothrombin) and VII (proconvertin).
Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other skin conditions such as eczema.
A number of clinical studies have been conducted to investigate possible adverse events of this fixed combination corticosteroid and vitamin D analog.