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In humans, mitochondrial DNA (mtDNA) forms closed circular molecules that contain 16,569 [4] [5] DNA base pairs, [6] with each such molecule normally containing a full set of the mitochondrial genes. Each human mitochondrion contains, on average, approximately 5 such mtDNA molecules, with the quantity ranging between 1 and 15. [6]
Mechanisms for this include simple dilution (an egg contains on average 200,000 mtDNA molecules, whereas a healthy human sperm has been reported to contain on average 5 molecules), [43] [44] degradation of sperm mtDNA in the male genital tract and in the fertilized egg; and, at least in a few organisms, failure of sperm mtDNA to enter the egg.
Each human cell contains approximately 100 mitochondria, giving a total number of mtDNA molecules per human cell of approximately 500. [35] However, the amount of mitochondria per cell also varies by cell type, and an egg cell can contain 100,000 mitochondria, corresponding to up to 1,500,000 copies of the mitochondrial genome (constituting up ...
Pages in category "Human mtDNA haplogroups" The following 55 pages are in this category, out of 55 total. This list may not reflect recent changes. ...
(b) Counts of haplogroups in table format. For populations details, see 1000 Genomes Project#Human genome samples. In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree.
The hair follicle is an organ found in mammalian skin. [1] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions.. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells
Haplogroup M is a human mitochondrial DNA (mtDNA) haplogroup.An enormous haplogroup spanning all the continents, the macro-haplogroup M, like its sibling the macro-haplogroup N, is a descendant of the haplogroup L3.
Haplogroup R is a widely distributed human mitochondrial DNA (mtDNA) haplogroup. Haplogroup R is associated with the peopling of Eurasia after about 70,000 years ago, and is distributed in modern populations throughout the world outside of sub-Saharan Africa. [4] Haplogroup R is a descendant of the macro-haplogroup N.