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Metformin does not cause kidney damage by itself, however there is a risk of serious side effects if metformin is used when you have impaired renal function, Dr. Gupta notes.
It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet, Janumet XR). [8] Common side effects include headaches, swelling of the legs, and upper respiratory tract infections. [8] Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain. [8]
It may be used in those whose blood sugar is not controlled with metformin and a sulfonylurea. [10] [11] It is taken by mouth. [10] Common side effects include diarrhea, headache, and upper respiratory tract infections. [5] Serious side effects may include lactic acidosis, pancreatitis, low blood sugar, heart failure, joint pain, and allergic ...
Stomach pain. Lightheadedness. Muscle pain. Shortness of breath. Weakness. Hypoglycemia. ... Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset stomach. Taking ...
Common adverse effects include diarrhea, nausea, and abdominal pain. [16] It has a small risk of causing low blood sugar. [16] High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. [23] [24] Metformin is a biguanide anti-hyperglycemic agent. [16]
Metformin is the most commonly prescribed oral drug for diabetes. Of course, if you or a loved one receives treatment for diabetes, you probably already knew this. 7 Benefits of Metformin ...
A 2020 Cochrane systematic review did not find enough evidence of reduction of all-cause mortality, serious adverse events, cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke or end-stage renal disease when comparing metformin monotherapy to dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes.
Age. The risk of most causes of joint pain increases with age. This may be due to increased wear and stress on joints over time and a higher likelihood of other underlying medical conditions ...