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  2. Thrombotic thrombocytopenic purpura - Wikipedia

    https://en.wikipedia.org/wiki/Thrombotic...

    Due to the high mortality of untreated TTP, a presumptive diagnosis of TTP is made even when only microangiopathic hemolytic anemia and thrombocytopenia are seen, and therapy is started. Transfusion is contraindicated in thrombotic TTP, as it fuels the coagulopathy. Since the early 1990s, plasmapheresis has become the treatment of choice for TTP.

  3. Caplacizumab - Wikipedia

    https://en.wikipedia.org/wiki/Caplacizumab

    On 30 August 2018, it was approved in the European Union for the "treatment of adults experiencing an episode of acquired thrombotic thrombocytopenic purpura (aTTP), in conjunction with plasma exchange and immunosuppression". [10] It is an anti-von Willebrand factor humanized immunoglobulin. [11]

  4. Apadamtase alfa - Wikipedia

    https://en.wikipedia.org/wiki/Apadamtase_alfa

    Apadamtase alfa, sold under the brand name Adzynma, is an enzyme replacement therapy used for the treatment of thrombotic thrombocytopenic purpura. [1] Apadamtase alfa is a human recombinant a disintegrin and metalloproteinase with thrombospondin motifs 13. [1] It is given by injection into a vein. [1]

  5. Thrombocytopenic purpura - Wikipedia

    https://en.wikipedia.org/wiki/Thrombocytopenic_purpura

    Another form is thrombotic thrombocytopenic purpura. [citation needed] Diagnosis ... Treatment. This section is empty. You can help by adding to it.

  6. Thrombocytopenia - Wikipedia

    https://en.wikipedia.org/wiki/Thrombocytopenia

    Treatment of thrombotic thrombocytopenic purpura (TTP) is a medical emergency, since the associated hemolytic anemia and platelet activation can lead to kidney failure and changes in the level of consciousness. Treatment of TTP was revolutionized in the 1980s with the application of plasmapheresis.

  7. Cryosupernatant - Wikipedia

    https://en.wikipedia.org/wiki/Cryosupernatant

    Cryosupernatant plasma can be used when replacement of FVIII is not required, [2] and is indicated for plasma exchange for patients with thrombotic thrombocytopenic purpura (TTP) [1] as well as for treatment of hemolytic-uremic syndrome (HUS) by plasma exchange, when plasma exchange is indicated. [3]

  8. List of antineoplastic agents - Wikipedia

    https://en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Osteoporosis, including drug- and cancer-related osteoporosis, giant cell tumour of bone and hypercalcaemia of malignancies: Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin: IV: CD33 antibody that induces apoptosis of the tagged cell. Acute myeloid leukaemia

  9. Thrombotic microangiopathy - Wikipedia

    https://en.wikipedia.org/wiki/Thrombotic_microangiopathy

    Thrombotic microangiopathy (TMA) is a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury. [1] It may be seen in association with thrombocytopenia, anemia, purpura and kidney failure. The classic TMAs are hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.

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