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Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count , low red blood cells due to their breakdown , and often kidney , heart , and brain dysfunction. [ 1 ]
Radiation therapy is commonly used in prostate cancer treatment. It may be used instead of surgery or after surgery in early-stage prostate cancer (adjuvant radiotherapy). Radiation treatments also can be combined with hormonal therapy for intermediate risk disease, when surgery or radiation therapy alone is less likely to cure the cancer.
Prostate cancer: Myelosuppression, diarrhoea, kidney failure, hypersensitivity, severe GI reactions (including perforation, ileus, colitis, etc.; all rare) and peripheral neuropathy Docetaxel: IV: As above. Breast cancer, non-small cell lung cancer, ovarian cancer, prostate cancer, squamous cell head and neck cancer and gastric cancer.
On 30 August 2018, it was approved in the European Union for the "treatment of adults experiencing an episode of acquired thrombotic thrombocytopenic purpura (aTTP), in conjunction with plasma exchange and immunosuppression". [10] It is an anti-von Willebrand factor humanized immunoglobulin. [11]
The efficacy of apadamtase alfa in the prophylactic treatment of participants with congenital thrombotic thrombocytopenic purpura was evaluated in 46 participants who were randomized to receive six months of treatment with either apadamtase alfa or plasma based therapies (Period 1), then crossed over to the other treatment for six months (Period 2). [5]
thrombotic thrombocytopenic purpura, thrombosis: Casirivimab [29] mab: human: spike protein receptor binding domain (RBD) of SARS-CoV-2: Yes when used with imdevimab [45] [46] COVID-19: Capromab [32] Prostascint: mab: mouse: Glutamate carboxypeptidase II: Y: prostate cancer (detection) Carlumab [16] mab: human: MCP-1: oncology/immune ...
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