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Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
The radioactivity concentration is measured from the PET or SPECT images for the various organs of interest. This may include measuring the volume of these organs e.g. from the CT image (rather than weighing the organs as in the dissection procedure) or assessing the radioactivity concentration in a representative part of the organ.
Positron emission tomography–computed tomography (better known as PET-CT or PET/CT) is a nuclear medicine technique which combines, in a single gantry, a positron emission tomography (PET) scanner and an x-ray computed tomography (CT) scanner, to acquire sequential images from both devices in the same session, which are combined into a single superposed (co-registered) image.
PET is a functional imaging technique that produces a three-dimensional image of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron -emitting radionuclide ( tracer ), which is introduced into the body on a biologically active molecule.
DOTA linked to the monoclonal antibody tacatuzumab and chelating yttrium-90 Whole-body PET scan using 18 F-FDG showing intestinal tumors and non-specific accumulation in bladder Radiolabeling is a technique used to track the passage of a molecule that incorporates a radioisotope through a reaction, metabolic pathway, cell, tissue, organism, or ...
SeHCAT is a taurine-conjugated bile acid analog which was synthesized for use as a radiopharmaceutical to investigate in vivo the enterohepatic circulation of bile salts. [2] By incorporating the gamma-emitter 75 Se into the SeHCAT molecule, the retention in the body or the loss of this compound into the feces could be studied easily using a standard gamma camera, available in most clinical ...
Scandium-44 (44 Sc) is a radioactive isotope of scandium that decays by positron emission to stable 44 Ca with a half-life of 4.042 hours.. 44 Sc can be obtained as a daughter radionuclide of long-lived 44 Ti (t 1/2 60.4 a) from 44 Ti / 44 Sc generator or can be produced by nuclear reaction 44 Ca ( p, n) 44 Sc in small cyclotrons.
For a bone scan, the patient is injected with a small amount of radioactive material, such as 700–1,100 MBq (19–30 mCi) of 99m Tc-medronic acid and then scanned with a gamma camera. Medronic acid is a phosphate derivative which can exchange places with bone phosphate in regions of active bone growth, so anchoring the radioisotope to that ...
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