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Carvedilol is a basic, hydrophobic compound with a steady-state volume of distribution of 115 L. Plasma clearance ranges from 500 to 700 mL/min. [27] Carvedilol is highly lipophilic and easily crosses the blood–brain barrier in animals, and hence is not thought to be peripherally selective.
A follow-up period of at least 10-15 years would be ideal to better evaluate long-term associations between antibiotic use and cognitive decline, as dementia and cognitive impairments often ...
A new study found the biggest risk factors and predictors at 60 for dementia at 80. Neurologists weigh in on the research and share ways to prevent dementia.
The term "steroid dementia" was coined by Varney et al. (1984) in reference to the effects of long-term glucocorticoid use in 1,500 patients. [3] While the condition generally falls under the classification of Cushing's syndrome , the term "steroid dementia syndrome" is particularly useful because it recognizes both the cause of the syndrome ...
Therefore, early and accurate diagnosis of dementia and staging can be essential to proper clinical care. Without the ability to reliably assess dementia across the board, the misuse of anti-dementia compounds could have negative consequences, such as patients receiving the wrong medication, or not receiving treatment in the early stages of ...
An estimated 5.8 million people in the U.S. have Alzheimer’s disease and related dementias, but the condition can be tricky to diagnose.Patients usually are put through a series of tests, and it ...
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Alzheimer's disease is the most common form of dementia, affecting more than three million Americans per year. And while its exact cause is unknown, researchers may have just had a breakthrough.