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In chemical biology, tonicity is a measure of the effective osmotic pressure gradient; the water potential of two solutions separated by a partially-permeable cell membrane. Tonicity depends on the relative concentration of selective membrane-impermeable solutes across a cell membrane which determine the direction and extent of osmotic flux .
Ringer's lactate solution is commonly used for fluid resuscitation after blood loss due to trauma, or surgery. [9] [10]It is extensively used in aggressive volume resuscitation, e.g. for patients with pancreatitis, hemorrhagic shock or major burn injuries. [10]
Intravenous sugar solution, also known as dextrose solution, is a mixture of dextrose (glucose) and water. [1] It is used to treat low blood sugar or water loss without electrolyte loss. [ 2 ] Water loss without electrolyte loss may occur in fever , hyperthyroidism , high blood calcium , or diabetes insipidus . [ 2 ]
Osmolarity and tonicity are related but distinct concepts. Thus, the terms ending in -osmotic (isosmotic, hyperosmotic, hypoosmotic) are not synonymous with the terms ending in -tonic (isotonic, hypertonic, hypotonic). The terms are related in that they both compare the solute concentrations of two solutions separated by a membrane.
In the clinical setting, there are two types of fluids that are used for intravenous drips: crystalloids and colloids. Crystalloids are aqueous solutions of mineral salts or other water-soluble molecules. Colloids contain larger insoluble molecules, such as gelatin.
Osmosis in a U-shaped tube. Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane. [1]
Plasma osmolality measures the body's electrolyte–water balance. [1] There are several methods for arriving at this quantity through measurement or calculation. Osmolality and osmolarity are measures that are technically different, but functionally the same for normal use.
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.