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Expressed as a percentage, the oxygen saturation is the ratio of the amount of oxygen bound to the hemoglobin, to the oxygen-carrying capacity of the hemoglobin. The oxygen-carrying capacity of hemoglobin is determined by the type of hemoglobin present in the blood. The amount of oxygen bound to the hemoglobin at any time is related, in large ...
Hemoglobin increases the oxygen-carrying capacity of blood by about 40-fold, [62] with the ability of hemoglobin to carry oxygen influenced by the partial pressure of oxygen in the local environment, a relationship described in the oxygen–hemoglobin dissociation curve. When the ability of hemoglobin to carry oxygen is degraded, a hypoxic ...
Assuming a hemoglobin concentration of 15 g/dL and an oxygen saturation of 99%, the oxygen concentration of arterial blood is approximately 200 mL of O 2 per L. The saturation of mixed venous blood is approximately 75% in health. Using this value in the above equation, the oxygen concentration of mixed venous blood is approximately 150 mL of O ...
Using the fact that each gram of hemoglobin can carry 1.34 mL of O2, the oxygen content of the blood (either arterial or venous) can be estimated by the following formula: = [] ( /) + PO2 is the partial pressure of oxygen and reflects the amount of oxygen gas dissolved in the blood. The term 0.0032 * P02 in the equation is very small and ...
Hemoglobin has an oxygen-binding capacity of 1.34 mL of O 2 per gram, [6] which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. [7] The mammalian hemoglobin molecule can bind and transport up to four oxygen molecules. [8] Hemoglobin also transports other gases.
The alveolar gas equation is the method for calculating partial pressure of alveolar oxygen (p A O 2). The equation is used in assessing if the lungs are properly transferring oxygen into the blood. The alveolar air equation is not widely used in clinical medicine, probably because of the complicated appearance of its classic forms.
Oxygen transmission rate (OTR) is the measurement of the amount of oxygen gas that passes through a substance over a given period. It is mostly carried out on non-porous materials, where the mode of transport is diffusion, but there are a growing number of applications where the transmission rate also depends on flow through apertures of some description.
The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body. A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2.