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Corticobasal degeneration (CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
Corticobasal syndrome (CBS) is a rare, progressive atypical Parkinsonism syndrome and is a tauopathy related to frontotemporal dementia. [ 1 ] [ 2 ] CBS is typically caused by the deposit of tau proteins forming in different areas of the brain.
The poor prognosis is predominantly attributed to the serious impact this condition has on the quality of life. [3] The average age at symptoms onset is 63 and survival from onset averages seven years with a wide variance. [55] Pneumonia is a frequent cause of death, often caused by accidental aspiration of food particles. [56]
Survival rate is a part of survival analysis.It is the proportion of people in a study or treatment group still alive at a given period of time after diagnosis. It is a method of describing prognosis in certain disease conditions, and can be used for the assessment of standards of therapy.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
A 2019 meta-analysis found an average survival time after diagnosis of 4.1 years [8] —indicating survival in DLB 1.6 years less than after a diagnosis of Alzheimer's. [211] A 2017 review found survival from disease onset between 5.5 and 7.7 years, and survival from diagnosis between 1.9 and 6.3 years.
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Parkinson-plus syndromes (PPS) are a group of neurodegenerative [1] diseases featuring the classical features of Parkinson's disease (tremor, rigidity, akinesia/bradykinesia, and postural instability) with additional features that distinguish them from simple idiopathic Parkinson's disease (PD).