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  2. Ropeginterferon alfa-2b - Wikipedia

    en.wikipedia.org/wiki/Ropeginterferon_alfa-2b

    Ropeginterferon alfa-2b can cause liver enzyme elevations, low levels of white blood cells, low levels of platelets, joint pain, fatigue, itching, upper airway infection, muscle pain and flu-like illness. [3] Side effects may also include urinary tract infection, depression and transient ischemic attacks (stroke-like attacks). [3]

  3. Peginterferon alfa-2b - Wikipedia

    en.wikipedia.org/wiki/Peginterferon_alfa-2b

    Pegylated interferon alfa-2b is a drug used to treat melanoma, as an adjuvant therapy to surgery. [3] Also used to treat hepatitis C (typically, in combination with ribavarin), it is no longer recommended due to poor efficacy and adverse side-effects. [4] Subcutaneous injection is the preferred delivery method. [3]

  4. Interferon alfa-2b - Wikipedia

    en.wikipedia.org/wiki/Interferon_alfa-2b

    Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and produced recombinantly in E. coli [ 1 ] in the laboratory of Charles Weissmann at the University of Zurich , in 1980.

  5. Interferon alfa - Wikipedia

    en.wikipedia.org/wiki/Interferon_alfa

    Interferon alfa or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography.

  6. IFNA2 - Wikipedia

    en.wikipedia.org/wiki/IFNA2

    The gene encoding IFNα2, the IFNA2 gene, is clustered with all other type I IFN genes on chromosome 9 [8] and as all type I IFN genes, it is devoid of intron. [9] The open reading frame (coding sequence) of IFNA2 codes for a pre-protein of 188 amino acids with a 23 amino acid signal peptide allowing secretion of the mature protein.

  7. Simeprevir - Wikipedia

    en.wikipedia.org/wiki/Simeprevir

    Simeprevir is administered as one capsule once daily with pegylated interferon and ribavirin for the treatment of genotype 1 or genotype 4 chronic hepatitis C in adult people with compensated liver disease (including cirrhosis), with or without HIV-1 co-infection, who are treatment naive or who have failed previous interferon therapy.

  8. Interferon - Wikipedia

    en.wikipedia.org/wiki/Interferon

    Interferon alfa: Multiferon Interferon alpha 2a: Roferon A Interferon alpha 2b: Intron A/Reliferon/Uniferon Human leukocyte Interferon-alpha (HuIFN-alpha-Le) Multiferon Interferon beta 1a, liquid form: Rebif Interferon beta 1a, lyophilized: Avonex Interferon beta 1a, biogeneric (Iran) Cinnovex Interferon beta 1b: Betaseron / Betaferon ...

  9. TNF inhibitor - Wikipedia

    en.wikipedia.org/wiki/TNF_inhibitor

    A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...