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A better estimate is provided by the total area of the cross-sections perpendicular to the muscle fibers (green lines in figure 1). This measure is known as the physiological cross-sectional area (PCSA), and is commonly calculated and defined by the following formula, developed in 1975 by Alexander and Vernon: [4] [5] [6]
Muscles with short fibers will have higher PCSA per unit muscle mass, thus greater force production, while muscle with long fibers will have lower PCSA per unit muscle mass, thus lower force production. However, muscles with longer fibers will shorten at greater absolute speeds than a similar muscle with shorter fibers. [2]
The muscular layer (muscular coat, muscular fibers, muscularis propria, muscularis externa) is a region of muscle in many organs in the vertebrate body, adjacent to the submucosa. It is responsible for gut movement such as peristalsis .
A myofibril (also known as a muscle fibril or sarcostyle) [1] is a basic rod-like organelle of a muscle cell. [2] Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. [3] Each myofibril has a diameter of 1–2 micrometres. [3]
At each end of the muscle fibre, the surface layer of the sarcolemma fuses with a tendon fibre, and the tendon fibres, in turn, collect into bundles to form the muscle tendons that adhere to bones. The sarcolemma generally maintains the same function in muscle cells as the plasma membrane does in other eukaryote cells. [4]
Each muscle fiber contains sarcolemma, sarcoplasm, and sarcoplasmic reticulum. The functional unit of a muscle fiber is called a sarcomere. [2] Each muscle cell contains myofibrils composed of actin and myosin myofilaments repeated as a sarcomere. [3] Many nuclei are present in each muscle cell placed at regular intervals beneath the sarcolemma.
The muscle fibers belonging to one motor unit can be spread throughout part, or most of the entire muscle, depending on the number of fibers and size of the muscle. [2] [3] When a motor neuron is activated, all of the muscle fibers innervated by the motor neuron are stimulated and contract. The activation of one motor neuron will result in a ...
The endomysium, meaning within the muscle, is a wispy layer of areolar connective tissue that ensheaths each individual muscle fiber, or muscle cell. [1] [2] [3] It also contains capillaries and nerves. It overlies the muscle fiber's cell membrane: the sarcolemma. Endomysium is the deepest and smallest component of muscle connective tissue.