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Medically unexplained physical symptoms (MUPS or MUS) are symptoms for which a treating physician or other healthcare providers have found no medical cause, or whose cause remains contested. [1] In its strictest sense, the term simply means that the cause for the symptoms is unknown or disputed—there is no scientific consensus .
The main symptom is "post-exertional neuroimmune exhaustion" (PENE), which encompasses fatigability, symptoms worsening after exertion, exhaustion after exertion, a prolonged recovery from activity, and reduction of activities due to symptoms. The ICC definition describes severity levels: Mild ME is described as roughly a 50% in functioning ...
A diagnosis for children often requires a shorter symptom duration. For example, the CCC definition only requires three months of persistent symptoms in children compared to six months for adults. [10]: 17–18 NICE requires only four weeks of symptoms to suspect ME/CFS in children, compared to six weeks in adults.
ICF differs from other forms of chronic fatigue since it is unexplained rather than linked to a medical or psychological illness (for example, diabetes or depression). [6] This means that ICF patients have reduced treatment options: there is no underlying disease or known cause that could be treated in order to reduce the degree of fatigue ...
Functional somatic syndrome (FSS) is any of a group of chronic diagnoses with no identifiable organic cause.This term was coined by Hemanth Samkumar. [citation needed] It encompasses disorders such as fibromyalgia, chronic widespread pain, temporomandibular disorder, irritable bowel syndrome, [1] lower back pain, tension headache, atypical face pain, non-cardiac chest pain, insomnia ...
IBS symptoms in women can also be triggered or worsened by menstruation, though the reason why isn't completely clear. Stress can also spark symptoms of IBS. "Some people say the GI tract is a ...
Some investigations suggest people can recover; the natural history of the illnesses implies that around 50% to 75% of patients with medically unexplained symptoms improve, whereas 10% to 30% deteriorate. Fewer physical symptoms and better baseline functioning are stronger prognostic indicators. A strong, positive relationship between the ...
An example of such a diagnosis is "fever of unknown origin": to explain the cause of elevated temperature the most common causes of unexplained fever (infection, neoplasm, or collagen vascular disease) must be ruled out. Other examples include: Fibromyalgia [9] Adult-onset Still's disease [10] Behçet's disease [11] Bell's palsy [12]