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Endocrine disruptors are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones. They are sometimes also referred to as hormonally active agents , endocrine disrupting chemicals , or endocrine disrupting compounds .
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
The 2011 EDC additions were made in consultation with TEDX, the US endocrine-disruption research NGO founded by Professor Theo Colborn, and coincided with EU plans over 2011–2012 to develop accepted criteria for identifying endocrine disrupting chemicals. [6] In October 2014, the list was updated, this time with 28 new chemicals.
Endocrine disruptors are chemicals that interfere with our endocrine systems, which control the body’s hormones—such as insulin, testosterone, and estrogen—and numerous bodily functions ...
Xenoestrogens are also called "environmental hormones" or "EDC" (Endocrine Disrupting Compounds, or Endocrine disruptor for short). Most scientists that study xenoestrogens, including The Endocrine Society , regard them as serious environmental hazards that have hormone disruptive effects on both wildlife and humans.
In the United States, the Endocrine Disruptor Screening and Testing Advisory Committee was formed in 1996 and developed the Endocrine Disruptor Screening Program (EDSP). [ 30 ] [ 31 ] The EDSP is used by the EPA and other regulatory bodies to screen chemicals such as pesticides and potential environmental pollutants for their effects on the ...
Thousands of scientific articles have since been published on endocrine disruption, demonstrating the availability of grant money for research on the hypothesis raised by Our Stolen Future. For example, a symposium at the 2007 American Association for the Advancement of Science (AAAS) meeting explored the contribution of endocrine disruption to ...
BPA is an example of an endocrine disruptor which negatively affects reproductive development by acting as an estrogen mimicker (xenoestrogen) and a likely androgen mimicker. [46] Bisphenol A exposure in fetal female rats leads to mammary gland morphogenesis , increased formation of ovarian tumors , and increased risk of developing mammary ...