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When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [116] and $13 billion a year at its peak, [117] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years." [116]
[5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34] This could be due to the statins inhibiting the enzyme (HMG-CoA reductase), which is necessary to make cholesterol, but also for other processes, such as CoQ 10 production, which ...
Taking medications like blood pressure and lipid-lowering drugs for more than 5 years is associated with a lower incidence of dementia, a new study has found. ... The study analyzed data from over ...
Age can affect the choice of medications. Current UK guidelines suggest starting patients over the age of 55 years first on calcium channel blockers or thiazide diuretics. Age and multi-morbidity can affect the choice of medication, the target blood pressure and even whether to treat or not. [61] Anxiety may be improved with the use of beta ...
You’ve likely heard your health care provider say your blood pressure is something like “120 over 80,” typically a larger number over a smaller number. Together, the two are measured in ...
The normal range of GFR, adjusted for body surface area, is 100–130 average 125 (mL/min)/(1.73 m 2) in men and 90–120 (mL/min)/(1.73 m 2) in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 (mL/min)/(1.73 m 2) until 2 years of age in both sexes, and then it progressively decreases. After age 40, GFR ...