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When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
[5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34] This could be due to the statins inhibiting the enzyme (HMG-CoA reductase), which is necessary to make cholesterol, but also for other processes, such as CoQ 10 production, which ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. ... on a patient’s age, diabetes, blood pressure and ...
A 2019 survey found that globally, we think old age begins at 66. When asked to describe it, we usually use the term wise (35%), followed by frail (32%), lonely (30%), and respected (25%). People ...
From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [116] and $13 billion a year at its peak, [117] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years." [116]
≈100% (>65 years old) [7] Atherosclerosis [ a ] is a pattern of the disease arteriosclerosis , [ 8 ] characterized by development of abnormalities called lesions in walls of arteries . This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [ 9 ]
Taking medications like blood pressure and lipid-lowering drugs for more than 5 years is associated with a lower incidence of dementia, a new study has found. ... from over 88,000 people with ...