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Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [ 1 ] [ 2 ] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [ 3 ]
However, clinical, laboratory data, and imaging can all help with the diagnosis.[8] First and foremost, patients present with symptoms of hypopituitarism and must undergo pituitary hormone function evaluation. [1] Biopsy is the only means of accurate diagnosis as no autoantigen has been discovered.
Sheehan's syndrome, also known as postpartum pituitary gland necrosis, occurs when the pituitary gland is damaged due to significant blood loss and hypovolemic shock (ischemic necrosis) or stroke, originally described during or after childbirth leading to decreased functioning of the pituitary gland (hypopituitarism). [1]
PSIS is a common cause of congenital hypopituitarism, and causes a permanent growth hormone deficit. Some PSIS-affected individuals may also present with adrenal hypoplasia (5–29%), diabetes insipidus (5–29%), primary amenorrhea (5–29%), hypothyroidism (30–79%), failure to thrive (80–99%), septooptic dysplasia (5–29%), and Fanconi ...
Hypopituitarism (or Panhypopituitarism) Pituitary tumors. Pituitary adenomas; ... List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and ...
After an episode of pituitary apoplexy, 80% of people develop hypopituitarism and require some form of hormone replacement therapy. [1] [2] The most common problem is growth hormone deficiency, which is often left untreated [1] [4] but may cause decreased muscle mass and strength, obesity and fatigue.
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It was shown through various testing that administration of bromocriptine can improve field of vision defects and lower prolactin levels. It was also found that when using corticosteroids, there was a decrease in size of the gland, and relieved compression on the dura mater.