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Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. [7] It is used primarily to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.
The REMS program developed out of previous systems dating back to the 1980s for monitoring the use of a small number of high-risk drugs such as isotretinoin, which causes serious birth defects; clozapine, which can cause agranulocytosis; and thalidomide, which is used to treat leprosy and certain cancers but causes serious birth defects. [4]
As clozapine suppresses the development of bone marrow, in turn reducing white blood cells which can lead to infection, blood tests are taken for the first six months on this medication. [19] The risk of experiencing agranulocytosis due to clozapine treatment is higher in elderly people, children, and adolescents. [16]
ReVia – an opioid antagonist primarily used in the management of alcohol dependence, opioid dependence or other impulse control/addictive behaviors such as habitual self-mutilation; Rexulti (brexpiprazole) – atypical antipsychotic used to treat mood and psychotic disorders
However, the risk of serious adverse effects from clozapine is low, and there are the beneficial effects to be gained of a reduced risk of suicide, and aggression. [ 120 ] [ 121 ] Typical antipsychotics and atypical risperidone can have a side effect of sexual dysfunction. [ 122 ]
Cauliflower can also increase how quickly the liver breaks down medications like clozapine (used to treat schizophrenia), pentazocine (used to treat nerve pain), theophylline (used to treat asthma ...
Atypical antipsychotics are considered lower-risk for causing TD than their typical counterparts, with incidence rates of 13.1% and 32.4% respectively in short-term trials primarily utilising Haloperidol as the typical antipsychotic. [25] Quetiapine and clozapine are considered the lowest risk agents for precipitating TD. [25]
We checked in with several dietitians to find out which canned foods they recommend for weight loss and weight management. Here are their top picks. Canned Artichoke Hearts.