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The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 subtype of the influenza A virus.
[58] The season's poor harvests and hunger in the Spanish population, [59] as well as negligent medical care, likely contributed to the severity of the influenza pandemic in Spain. Flu symptoms could be so intense that the region's physicians often distinguished it from other contagious, seasonal pneumonias that spread from East Europe. [60]
The 1918 influenza pandemic has been declared, according to Barry's text, as the 'deadliest plague in history'. The extensiveness of this declaration can be supported through the following statements: "the greatest medical holocaust in history" [2] and "the pandemic ranks with the plague of Justinian and the Black Death as one of the three most destructive human epidemics". [3]
The sequences of the polymerase proteins (PA, PB1, and PB2) of the 1918 virus and subsequent human viruses differ by only 10 amino acids from the avian influenza viruses. Viruses with 7 of the 10 amino acids in the human influenza locations have already been identified in currently circulating H5N1 .
The 1918 flu pandemic, commonly referred to as the Spanish flu, was a category 5 influenza pandemic caused by an unusually severe and deadly Influenza A virus strain of subtype H1N1. The difference between the influenza mortality age-distributions of the 1918 epidemic and normal epidemics.
H5N1 is a type of influenza virus that causes highly infectious and severe respiratory disease in birds. Outbreaks of the H5N1 avian influenza virus in wild birds and poultry have been ongoing in ...
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During the pandemic, 72 of the town's 80 residents perished from the flu. In his search, he unearthed bodies but failed to find any live viruses. [7] Nearly 50 years later, in July 1997, Hultin read an article in the journal Science written by virologist Jeffery Taubenberger who published the initial genetic sequence of the 1918 flu virus. [8]