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However, most infections with M. tuberculosis do not cause disease, [169] and 90–95% of infections remain asymptomatic. [87] In 2012, an estimated 8.6 million chronic cases were active. [170] In 2010, 8.8 million new cases of tuberculosis were diagnosed, and 1.20–1.45 million deaths occurred (most of these occurring in developing countries).
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Global tuberculosis cases reached an all-time high in 2023, with nearly 11 million people estimated to have become sick with the disease last year. According to the World Health Organization’s ...
Diagnostic methods that can identify influenza include viral cultures, antibody- and antigen-detecting tests, and nucleic acid-based tests. Treatment of influenza in cases of mild or moderate illness is supportive and includes anti-fever medications such as acetaminophen and ibuprofen , adequate fluid intake to avoid dehydration, and resting at ...
Tuberculosis can cause a cough that lasts longer than three weeks, coughing up blood and fever, and can be fatal if it's not treated properly, according to the CDC.
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M. tuberculosis can also grow on the lipid cholesterol as a sole source of carbon, and genes involved in the cholesterol use pathway(s) have been validated as important during various stages of the infection lifecycle of M. tuberculosis, especially during the chronic phase of infection when other nutrients are likely not available. [47]
Aspergilloma in an old tuberculosis cavity; healed, calcified tuberculous lesions are also present towards the right of the image Healed tuberculous cavity, where the entire left lung is destroyed. Post-tuberculosis lung disease (PTLD) is ongoing lung disease that is caused by tuberculosis (TB) but persists after the infection is cured. [1]