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Ganglioneuroma (occasionally called a "ganglioma") is a rare and benign tumor of the autonomic nerve fibers arising from neural crest sympathogonia (undifferentiated cells of the sympathetic nervous system). [1] However, ganglioneuromas themselves are fully differentiated neuronal tumors that do not contain immature elements. [2]
Ganglioneuroma (benign) Ganglioneuroblastoma (intermediate). Neuroblastoma (aggressive) See also. Neuroblastoma; References External links. This page was last edited ...
Ganglioneuroma - a tumor of the sympathetic nerve fibers arising from neural crest cells. [ 4 ] Pacinian neuroma - a very rare, painful, benign hyperplastic tumor of Pacinian corpuscles ( mechanoreceptors responsible for sensitivity to vibration and pressure ), sometimes linked to a history of local trauma .
MRI of a patient with anaplastic astrocytoma. The WHO classification of tumours of the central nervous system is a World Health Organization Blue Book that defines, describes and classifies tumours of the central nervous system (CNS).
Histologically, ganglioglioma is composed of both neoplastic glial and ganglion cells which are disorganized, variably cellular, and non-infiltrative. Occasionally, it may be challenging to differentiate ganglion cell tumors from an infiltrating glioma with entrapped neurons.
Most paragangliomas are asymptomatic, present as a painless mass, or create symptoms such as hypertension, tachycardia, headache, and palpitations. [3] While all contain neurosecretory granules, only in 1–3% of cases is secretion of hormones such as catecholamines abundant enough to be clinically significant; in that case manifestations often resemble those of pheochromocytomas (intra ...
Malignant ectomesenchymoma (MEM) is a rare tumor of soft tissues or the CNS, which is composed of both neuroectodermal elements [represented by ganglion cells and/or well-differentiated or poorly differentiated neuroblastic cells such as ganglioneuroma, ganglioneuroblastoma, neuroblastoma, peripheral primitive neuroectodermal tumors – PNET ...
Malignant peripheral nerve sheath tumor. Back skin, 65-year-old man. MPNST. Symptoms may include: Swelling in the extremities (arms or legs), also called peripheral edema; the swelling often is painless.