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Arterial spin labeling utilizes the water molecules circulating with the brain, and using a radiofrequency pulse, tracks the blood water as it circulates throughout the brain. After a period of time in microseconds (enough to allow the blood to circulate through the brain), a 'label' image is captured.
Magnetic resonance imaging (MRI) scans to assess brain structure, connectivity, and the extent of white matter disease; Positron emission tomography (PET) scans to assess how well the brain uses glucose, and the extent of amyloid plaques and tau tangles. Neuropathological examination if a participant dies and has consented to autopsy.
The first study of the human brain at 3.0 T was published in 1994, [13] and in 1998 at 8 T. [14] Studies of the human brain have been performed at 9.4 T (2006) [15] and up to 10.5 T (2019). [16] Paul Lauterbur and Sir Peter Mansfield were awarded the 2003 Nobel Prize in Physiology or Medicine for their discoveries concerning MRI.
The FMRIB Software Library, abbreviated FSL, is a software library containing image analysis and statistical tools for functional, structural and diffusion MRI brain imaging data. FSL is available as both precompiled binaries and source code for Apple and PC computers. It is freely available for non-commercial use.
The key to Phase-contrast MRI (PC-MRI) is the use of a bipolar gradient. [4] A bipolar gradient has equal positive and negative magnitudes that are applied for the same time duration. The bipolar gradient in PC-MRI is put in a sequence after RF excitation but before data collection during the echo time of the generic MRI modality.
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Functional connectivity MRI (fcMRI), which can include resting state fMRI and task-based MRI, might someday help provide more definitive diagnoses for mental health disorders such as bipolar disorder and may also aid in understanding the development and progression of post-traumatic stress disorder as well as evaluate the effect of treatment. [24]
Learn how to download and install or uninstall the Desktop Gold software and if your computer meets the system requirements.