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  2. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    In February 2020, a US trial showed safe CRISPR gene editing on three cancer patients. [38] In October 2020, researchers Emmanuelle Charpentier and Jennifer Doudna were awarded the Nobel Prize in Chemistry for their work in this field. [39] [40] They made history as the first two women to share this award without a male contributor. [41] [5]

  3. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  4. Yoshizumi Ishino - Wikipedia

    en.wikipedia.org/wiki/Yoshizumi_Ishino

    The "iap" gene in gut microbe E. coli was sequenced by Ishino and his colleagues in 1987. [6] As the DNA segment used was longer than the gene itself, they accidentally discovered a partial DNA sequence of then-unnamed CRISPR in the process, [7] which would eventually become the basis of CRISPR gene editing.

  5. CRISPR/Cas tools - Wikipedia

    en.wikipedia.org/wiki/CRISPR/Cas_Tools

    It has since been adopted for use as a tool in the genetic engineering of higher organisms. Designing an appropriate gRNA is an important element of genome editing with the CRISPR/Cas system. A gRNA can and at times does have unintended interactions ("off-targets") with other locations of the genome of interest.

  6. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  7. Intellia Therapeutics - Wikipedia

    en.wikipedia.org/wiki/Intellia_Therapeutics

    In June 2021, Intellia made history by announcing interim Phase 1 data for NTLA-2001, demonstrating the ability to precisely edit target cells within the body to treat genetic disease with a single intravenous infusion of CRISPR. This was the first time any human clinical data has been published for an in vivo gene editing therapeutic candidate.

  8. Editas Medicine Stock History: The Story Behind the CRISPR ...

    www.aol.com/news/editas-medicine-stock-history...

    Here's the story behind the biotech stock that could be the best way to profit from the discovery of the century: CRISPR-Cas9 gene editing.

  9. Victoria Gray - Wikipedia

    en.wikipedia.org/wiki/Victoria_Gray

    Victoria Gray was the first patient ever to be treated with the gene-editing tool CRISPR for sickle-cell disease. [1]This marked the initial indication that a cure is attainable for individuals born with sickle-cell disease and another severe blood disorder, beta-thalassemia.