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Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]
Neuroleptic-induced deficit syndrome is principally characterized by the same symptoms that constitute the negative symptoms of schizophrenia: emotional blunting, apathy, hypobulia, anhedonia, indifference, difficulty or total inability in thinking, difficulty or total inability in concentrating, lack of initiative, attention deficits, and desocialization. [2]
Pleurothotonus, commonly known as Pisa syndrome, is a rare neurological disorder which occurs due to prolonged exposure to antipsychotic drugs (which may also be referred to as neuroleptics). It is characterized by dystonia , and abnormal and sustained involuntary muscle contraction.
Extrapyramidal symptoms are a reason why subjects drop out of clinical trials of antipsychotics; of the 213 (14.6%) subjects that dropped out of one of the largest clinical trials of antipsychotics (the CATIE trial [Clinical Antipsychotic Trials for Intervention Effectiveness], which included 1460 randomized subjects), 58 (27.2%) of those ...
Neuroleptic medications (antipsychotics), metoclopramide [1] [2] Diagnostic method: Based on symptoms after ruling out other potential causes [1] Differential diagnosis: Huntington's disease, cerebral palsy, Tourette syndrome, dystonia [2] Prevention: Using lowest possible dose of neuroleptic medication [3] Treatment
The term neuroleptic is often used as a synonym for antipsychotic, even though – strictly speaking – the two terms are not interchangeable. Antipsychotic drugs are a subgroup of neuroleptic drugs, because the latter have a wider range of effects. [287] [288] Antipsychotics are a type of psychoactive or psychotropic medication. [289] [290]
Celine Dion has given her first TV interview since her diagnosis of Stiff Person Syndrome (SPS) in 2022, detailing the toll it’s taken on her life in NBC News’ hourlong special “Celine’s ...
Based on symptoms and situation [2] Differential diagnosis: Sepsis, anaphylaxis, serotonin syndrome, neuroleptic malignant syndrome [3] Prevention: Avoiding potential triggers in those susceptible [2] Treatment: Dantrolene, supportive care [4] Prognosis: Risk of death: 5% (treatment), 75% (no treatment) [3] Frequency